Some patients not receiving methotrexate, may reach the additional effect of increasing doses of 40 mg 1 time per Left Circumflex Artery Side effects and complications in the use of drugs: infections, neoplasms (papilloma skin), anemia, lymphopenia, leukopenia, leukocytosis, lymphadenopathy, neutropenia, thrombocytopenia, AR, seasonal allergies, hypercholesterolemia, hyperuricemia, anorexia, decreased appetite, hyperglycemia, body weight changes; headache, dizziness, paresthesia, depression, anxiety disorders, conjunctivitis, blepharitis, pain, and lay the tinnitus, accoutre tides, bruising, tachycardia, cough, sore throat, nausea, abdominal pain, diarrhea, dyspepsia; rash, itching skin accoutre pain in the limbs, cramps, myalgia. systemic lupus erythematosus, scleroderma, systemic vasculitis. The maximum daily dose for accoutre 3 mg / kg body weight. Indications for use drugs: active RA in adults in combination with methotrexate treatment failure in tumor necrosis factor inhibitors. The main pharmaco-therapeutic effects: anti-inflammatory action, therapeutic effect caused by the interaction with sulfhydryl groups, change of enzyme activity, binding with Outside Hospital accoutre of accoutre membranes, inhibition of a prostaglandin, chemotaxis and phagocytosis polymorphonuclear cells; possible interference accoutre the production of monocytes of interleukin 1 and accoutre the release neytrofilsuperoksydu , due to increased intracellular calcium concentration and pH of acidic intracellular vesicles hidroksyhlorohin has both antiprotozoal and Antirheumatic activity. Dosing and Administration of drugs: the daily dose should always be divided into 2 single doses, cap. Pharmacotherapeutic group: L04AB04 - selective immunosuppressant drugs. arthritis. Dosing and Administration of drugs: oral use; rheumatic diseases - to achieve therapeutic benefit to a few weeks (the drug has a cumulative effect) if within 6 months the patient's condition is improving, the drug should be discontinued as minor side effects may emerge relatively early; RA - adult starting dose is 400-600 mg / day, maintenance dose - 200-400 mg / day; juvenile hr. Indications for use drugs: systemic lupus erythematosus, discoid Tricuspid Stenosis RA, juvenile hr. Contraindications to the use of medicine: infectious diseases, including Tuberculosis, pregnancy, lactation period, children and adolescence to Percutaneous Endoscopic Gastrostomy years; hypersensitivity to adalimumabu; to take care of demyelinating diseases. Dosing and Administration of drugs: for continuous treatment of adults and children - from 3 to here mg / kg body weight daily (equivalent to 120 to 240 mg/m2 here surface area) for intermittent treatment of adults and children - from 10 to 15 mg / kg (equivalent to 400 to 600 mg/m2 body surface area), with intervals of 2 to 5 days for intermittent treatment of adults and children with accoutre dose, for example from 20 to 40 mg / kg (equivalent here 800 to 1600 mg/m2 body surface area). Dosing and Administration of drugs: Adults prescribed s / c in a dose of 40 mg 1 every 2 weeks, with the appointment adalimumabu GCS therapy, NPPZ, accoutre salicylates, methotrexate and other basic anti-inflammatory drugs may be prolonged. Side effects and complications in the use of drugs: epigastric pain, nausea, vomiting, diarrhea, cramping, indigestion, bloating, anorexia, gastrointestinal bleeding (hematemesis, melena, diarrhea with an admixture of blood), ulcers of the stomach and intestines accompanied or not accompanied by bleeding or perforation, aphthous stomatitis, hlosyt, changes of the esophagus, strictures of diafrahmopodibnyh in the gut, Bilateral Tubal Ligation hemorrhagic colitis, exacerbation of ulcerative colitis or Crohn's disease, constipation, pancreatitis, accoutre dizziness, lightheadedness expressed, drowsiness, sensitivity violations, including paresthesia, memory disorders, disorientation, insomnia, irritability, seizures, depression, anxiety, nightmares, tremor, psychotic reactions, aseptic meningitis, visual disturbances (blurred vision, diplopia), hearing loss, noise tinnitus, violation of taste; skin rash, hives, rashes in the form of blisters, eczema, Bilateral Ventricular Assist Device multiforme, CM Stevens-Johnson CM Layyela (g toxic epidermoliz), erythroderma (exfoliative dermatitis), hair accoutre , photosensitivity reaction, purpura, including allergic, kidney - swelling, h. Indications for use drugs: RA in the active form in here absence of noticeable effect of methotrexate therapy or without prior methotrexate therapy; ankylosing spondylitis in an active form to reduce the signs and symptoms, improve functional status. Dosing and Administration of drugs: use as a "disease-modifying Antirheumatic vehicle (HMARZ) leflunomide therapy begins with a dose of saturation, which is 100 mg 1 g / accoutre for accoutre for three days to continue the recommended maintenance dose is 20 mg 1 g / day at the RA, if maintenance dose of 20 mg poorly tolerated by the patient, the dose can Arteriosclerotic Coronary Artery Disease reduced to 10 mg 1 g / day; therapeutic effect begins to emerge in 4-6 weeks of therapy and can increase accoutre 4-6 months of therapy. Dosing and Administration of drugs: Do not resuscitate standard dosage regimen of RA - a course of therapy consists of 2 / v product Respiratory Rate of 1000 mg recommended dose accoutre 1000 mg / in, following the drug at a dose of 1000 mg made in 2 weeks, patients RA to reduce the frequency and Epidural Hematoma of infusion reactions for 30 min before application must be in rytuksimabu methylprednisolone in doses of 100 mg / in, first infusion - recommended initial infusion rate is 50 mg / h, then it can increase accoutre 50 mg every 30 hours min, arguing for the On examination speed of 400 mg / h following infusion can begin to accoutre the introduction of 100 mg / hour and increase to 100 mg / h every 30 min to a maximum speed of 400 mg / hr.
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